IL-12-Programmed Long-Term CD8+T Cell Responses Require STAT4

of April 30 , 2017 . This information is current as Responses Require STAT 4 T Cell + IL - 12 - Programmed Long - Term CD 8 Shrikant

of April 14 , 2017 . This information is current as Responses Require STAT 4 T Cell + IL - 12 - Programmed Long - Term CD 8

STAT 4 T Cell + IL - 12 - Programmed Long - Term CD 8

Induction of Mouse T Cell CCR5 A Mandatory Role for STAT4 in IL-12

Interleukin-12 (IL-12)/STAT4 Axis Is an Important Element for β-Cell Dysfunction Induced by Inflammatory Cytokines

Pathology driving β-cell loss in diabetes is poorly defined. Chronic subclinical inflammation is associated with β-cell dysfunction. Acute in vitro exposure of islets and β-cells to an inflammatory cytokine cocktail (IL-1β/TNF-α/IFN-γ) results in loss of cell function and viability. The contribution of each cytokine alone or in combination has been evaluated in homogeneous mouse β-cell lines an...